Let the image of the point $\mathrm{P}(0,-5,0)$ in the line $\frac{x-1}{2}=\frac{y}{1}=\frac{z+1}{-2}$ be the point R and the image of the point $\mathrm{Q}\left(0, \frac{-1}{2}, 0\right)$ in the line $\frac{x-1}{-1}=\frac{y+9}{4}=\frac{z+1}{1}$ be the point S . Then the square of the area of the parallelogram PQRS is $\_\_\_\_$ .